Table 3.

Percent differences [95% confidence intervals (CIs)] for endotoxin and glucan levels associated with type and flavor.

	Endotoxin				Glucan
	Unadjusted models		Adjusted model		Unadjusted models		Adjusted model
	% Difference	p-Value	% Difference	p-Value	% Difference	p-Value	% Difference	p-Value
Typea
Cartridge	66 ($-1$, 178)	0.06	23 ($-42$, 159)	0.6	4123 (1408, 11727)	$<0.001$	318 ($-10$, 1842)	0.07
E-liquid	Ref		Ref		Ref		Ref
Flavorb
Tobacco	$-26$ ($-64$, 50)	0.4	$-40$ ($-69$, 19)	0.1	2421 (391, 12845)	$<0.001$	1042 (184, 4489)	0.001
Menthol	$-27$ ($-65$, 52)	0.4	$-39$ ($-69$, 20)	0.2	822 (73, 4800)	0.01	350 (11, 1733)	0.04
Others	$-6$ ($-55$, 94)	0.9	$-19$ ($-58$, 56)	0.5	928 (93, 5363)	0.01	112 ($-45$, 710)	0.3
Fruit	Ref		Ref		Ref		Ref

Note: Sample levels below LOD are substituted by a half the LOD. LODs ranged from 0.1 to $1.6\text{EU}/\mathrm{mL}$ for endotoxin and from 0.0125 to $0.2\text{ng}/\mathrm{mL}$ for glucan. Ref, reference.

^aAdjusted for flavor and brand (A to J).

^bAdjusted for type and brand (A to J).