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. 2019 Apr 24;127(4):046002. doi: 10.1289/EHP4381

Figure 4.

Figures 4A, 4B, and 4C are graphs for all leukemias, acute lymphoblastic leukemia, and acute myeloid leukemia, respectively, plotting risk ration ranging between 1 and 4, 1 and 8; and 1 and 16, respectively, (y-axis), across benzene concentration ranging between 1 and 15 micrograms per cubic meter with increments of 5 (x-axis).

Dose–response meta-analysis of childhood leukemia risk from benzene exposure for (A) all leukemias (Crosignani et al. 2004; Heck et al. 2014; Houot et al. 2015; Janitz et al. 2017; Raaschou-Nielsen et al. 2018; Vinceti et al. 2012), (B) acute lymphoblastic leukemia only (Crosignani et al. 2004; Heck et al. 2014; Houot et al. 2015; Janitz et al. 2017; Raaschou-Nielsen et al. 2018; Vinceti et al. 2012), and (C) acute myeloid leukemia only (Heck et al. 2014; Houot et al. 2015; Janitz et al. 2017; Raaschou-Nielsen et al. 2018; Vinceti et al. 2012). Spline curve (black solid line) with 95% confidence limits (gray dashed lines). RR, risk ratio.