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. 2019 Apr 9;127(4):047002. doi: 10.1289/EHP3986

Figure 5.

Figure 5 consists of six box and whisker plots. The first three plot CMap Perturbagen Classes (y-axis) across connectivity score (x-axis) for three T A S sub sets (T A S greater than 0.2; T A S greater than 0.2; and T A S greater than 0.4) for carcinogens and noncarcinogens. The final three plot the same for genotoxicity and nongenotoxicants.

Connectivity scores of top Connectivity Map (CMap) Perturbagen classes with differential connectivity [false discovery rate (FDR)<0.05] to carcinogens vs. noncarcinogens and genotoxicants vs. nongenotoxicants grouped by transcriptional activity scores (TAS) subsets. The lower, middle, and upper hinges of box plots correspond to the 25th, 50th (median), and 75th percentiles, respectively. The upper and lower whiskers extend to the smaller and largest value at most 1.5 × IQR (interquartile range) from the hinge, and data points beyond the whiskers are represented as dots.