Table 2.
Comparative Analysis of Patients Who Underwent MSA Implant for Primary GERD and for Persistent/de novo GERD During the Same Time Period at a Single Institution
| Demographic and Clinical Characteristics | Standard (n = 63) | Post-Surgical (n = 4) | P |
|---|---|---|---|
| Age, years, mean ± SD | 51.4 ± 13.6 | 54.3 ± 11.6 | .723 |
| Male, no. (%) | 45 (71.4) | 2 (50) | .216 |
| BMI, mean ± SD | 25.5 ± 4.2 | 29.0 ± 2.6 | .108 |
| Symptoms duration, years, mean ± SD | 9.3 ± 7.2 | 4 ± 2.6 | .997 |
| Daily PPI dose (mg), mean ± SD | 20.6 ± 20.6 | 50 ± 26.4 | .073 |
| Duration PPI therapy, years, mean ± SD | 4.9 ± 6.3 | 12 ± 15.7 | .270 |
| GERD-HRQL, mean ± SD | 19.3 ± 6.3 | 18.7 ± 9.3 | .756 |
| Hiatus hernia, cm, mean ± SD | 2.1 ± 1.5 | 3 ± 1 | .246 |
| DeMeester score, mean ± SD | 31.2 ± 23.6 | 24 ± 2.7 | .695 |
| Los Angeles Grade, no. (%) | |||
| A | 5 (7.9) | 1 (25) | .252 |
| B | 3 (4.8) | 3 (75) | <.005 |
| C | 2 (3.2) | 0 (0.0) | 1.000 |
| D | 1 (1.6) | 0 (0.0) | 1.000 |
| Barrett's esophagus, no. (%) | 9 (14.2) | 1 (25) | 1.000 |
| Operative characteristics | |||
| Operative time, minutes, mean ± SD | 71.4 ± 27 | 206.7 ± 24.7 | <.005 |
| MSA device, no. beads, median (IQR) | 15 (2) | 16 (0) | <.05 |
| Full mediastinal dissection, no. (%) | 31 (49.2) | 4 (100) | .239 |
| Postoperative characteristics | |||
| Complications, no. (%) | 1 (1.6) | 1 (25) | .090 |
| In-hospital length of stay, days, mean ± SD | 2.5 ± 0.7 | 3.5 ± 0.7 | <.05 |
| Followup, months, median (IQR) | 11 (8) | 13 (3.5) | .199 |
| Explants, no. (%) | 0 (0.0) | 0 (0.0) | — |
| GERD-HRQL, mean ± SD | 2.3 ± 1.9 | 3 ± 1 | .444 |
B-II, Billroth II; BMI, body mass index; GERD-HRQL, gastroesophageal reflux disease–health-related quality of life, MSA, magnetic sphincter augmentation; PPI, proton-pump inhibitor; RYGB, Roux-en-Y Gastric bypass; SG, sleeve gastrectomy.