Fig. 3. Nicotine withdrawal increases Nox2 expression in the nucleus accumbens.
(A) Bar graph showing qPCR analysis of Nox isoforms (primarily expressed in the brain) in the nucleus accumbens of Sal, Nic, and WD mice. (i) Nox1, (ii) Nox2, and (iii) Nox4. (B) Bar graph showing qPCR analysis of Nox2 mRNA expression in the caudate putamen of Sal, Nic, and WD mice. [Compared to Sal—**P < 0.01; compared to Nic—###P < 0.001; (A and B) n = 12 to 24 per treatment group.]