Figure 3. Taste bud cell differentiation is impeded, but not always, in the absence of visceral innervation.

Sections through taste buds in the soft palate of wild types (A), Neurog2 KO (B,C) and Neurog1 KO (D) at E20.5 (P2), immunostained with the indicated antibodies. Kcnq1, Entpd2, Gnat3 and Trpm5 are occasionally detected in residual CK8⁺ cells of Neurog2 KO embryos. In Neurog1 KOs, taste buds contained the normal complement of markers. Scale bar: 20 μm.