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On the two sides of the figure, there are the GLS values, recorded before the onset of the therapy with sacubitril/valsartan (left side) and after a mean therapy duration of 14 ± 3 months (right side). Initial mean GLS value: -10.14 ± 3.08%; final mean GLS value: -18.23 ± 7.28% (P < 0.001) (paired samples t-test). GLS: global longitudinal strain.
