Figure 5:

Morphine withdrawal similarly altered mIPSCs in male and female mice. A) Representative traces of SN-M and MN-M mIPSCs. B) Representative tracels of SN-F and MN-F mIPSCs. C) Cumulative distribution plot comparing miniature-IPSC inter event interval in male mice (SN-M n=14; MN-M n=22). D) Cumulative distribution plot comparing miniature-IPSC inter event interval in female mice (SN-F n=17; MN-F n=19). E) Cumulative distribution plot comparing miniature-IPSC amplitude in male mice from the same cells as C F) Cumulative distribution plot comparing miniature-IPSC amplitude in female mice from the same cells as D. G) Bar graph of mIPSC frequency in male and female mice H) Bar graph of mIPSC amplitude in male and female mice**** (p<0.0001).