Figure 6:

Morphine withdrawal increases the paired-pulse ratio in male and female mice. A) Representative paired-pulse traces from BNST neurons in male mice (SN-M top; MN-M bottom, dashed line 0 pA, scale bar 100 pA x 25 ms). B) Representative paired-pulse traces from BNST neurons in female mice (SN-F, top; MN-F bottom, scale bar 50 pA x 10 ms). C). Bar graph of paired-pulse ratios (main effect of drug treatment, ** p<0.01; $ $ planned t-tests p<0.01, SN-M n=12; MN-M n=20, SN-F n=22; MN-F n=19). Each bar represents the mean ± SEM.