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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Transfusion. 2019 Aug 5;59(10):3102–3112. doi: 10.1111/trf.15467

Figure 1– Metabolic changes in RBCs prior to and after RCE with conventional or rejuvenated red blood cells.

Figure 1–

An overview of the experimental design (A) and partial least square-discriminant analysis (PLS-DA) of red blood cell (RBC – B) metabolic phenotypes in sickle cell anemia (SCA) patients prior to or 5h after RCE with standard or rejuvenated RBCs. In C, top 15 metabolites from the Variabile Importance in Projection plot. In D, top 50 metabolic changes by ANOVA.