Table 2.

Symptoms in the last follow‐up before initiation of enzyme replacement therapy

ID	Gender	Age at diagnosis	Neuropathic pain	Abdominal pain	Diarrhea	Clustered angiokeratoma	Sweating	Cornea verticillata	Threshold of hearing	Tinnitus	MSSI
1	M	15	Weekly	Monthly	Monthly	Yes	absent	no	<5	0	10
2	M	33	Weekly	Weekly	No	Yes	absent	N.A.	N.A.	N.A.	26
3	M	35	Daily	Weekly	Weekly	No	absent	yes	30	yes	18
4	M	36	No	Monthly	No	No	normal	yes	N.A.	N.A.	24
5	F	25	Weekly	Weekly	Weekly	No	reduced	N.A.	N.A.	N.A.	19
6	F	31	Weekly	Monthly	Monthly	No	normal	yes	15	no	5
7	F	46	no	Weekly	Weekly	No	reduced	no	25	no	10
8	F	48	No	No	No	No	normal	no	10	no	3
9	F	52	Daily	Weekly	Weekly	No	absent	yes	15	no	21
10	F	61	No	No	No	No	normal	N.A.	40	yes	10
11	F	60	Weekly	No	No	No	normal	no	20	yes	6
12	F	61	daily	No	No	No	reduced	yes	35	yes	30
13	F	66	no	No	<Monthly	No	absent	no	50	no	32
14	F	80	no	No	No	No	reduced	N.A.	N.A.	N.A.	N.A.

Abbreviations: F, female; M, male; MSSI, Mainz Severity Score Index; N.A, not available.