Table 1.

Summary of genetic variants of RT-112-LTT, J82-LTT, 253J-LTT, and T-24-LTT cells detected by exome sequencing.

Variants	RT-112-LTT	J82-LTT	253J-LTT	T-24-LTT
Overall number of mutations	12463	864	1602	4250
Number of genes	7479	720	1385	3373
Single base exchanges	11767	638	1354	3880
Double base exchanges	377	29	61	123
Insertions	139	71	60	88
Deletions	164	131	122	108
Single base deletions	90	65	59	91
Intronic	3300	280	463	1117
Exonic	7938	467	938	2760
UTR	708	84	136	213
Synonymous	2325	135	230	684
Nonsynonymous	4831	222	561	1740
Frameshift	116	49	39	73
Nonframeshift	292	37	63	109
Stop-gain	279	7	24	105
Unclassified/unknown	4615	414	685	1536