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Replication of rMuV-S79 in the cotton rats
| Groups | Viral replication in lung | |
|---|---|---|
| % infected animals | Viral titer (log10 PFU/g) | |
| rMuV-S79 | 100 | 2.68 ± 0.14 |
| Opti-MEM | 0 | Not detected |
Five cotton rats were inoculated with rMuV-S79 via intranasal route. Five cotton rats in control group were received the same volume of Opti-MEM without virus. Two groups of cotton rats were terminated at 4th day post-inoculation and viral titers in lung tissues were determined by plaque assay
