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. 2019 Aug 14;6(10):ofz364. doi: 10.1093/ofid/ofz364

Table 2.

Dosing Regimens of Antibiotics

Study Antibiotic Dose Frequency, % of (n)
Kutob (most common regimens reported) Amoxicillin/clavulanic acid (n = 30) 875/125 mg q12h 70
500/125 mg q8h 30
Amoxicillin (n = 12) 500 mg q8h 83
Cephalexin (n = 16) 500 mg q6h 56
Levofloxacin (n = 106) 500 mg q24h 48
750 mg q24h 33
Ciprofloxacin (n = 151) 500 mg q12h 84
TMP-SMX (n = 28) 800/160 mg q12h 100
Mercuro (doses for normal renal function only) Amoxicillin/clavulanic acid (n = 25) 875/125 mg q12h 92
500/125 mg q12h 4
500/125 mg q8h 4
Amoxicillin (n = 8) 1000 mg q8h 50
500 mg q8h 37.5
500 mg q12h 12.5
Cephalexin (n = 11) 500 mg q6h 82
500 mg q8h 9
500 mg q12h 9
Levofloxacin (n = 29) 500 mg q24h 13.7
750 mg q24h 82.7
Ciprofloxacin (n = 56) 500 mg q12h 91
750 mg q12h 7.1
Tamma Amoxicillin/clavulanic acid (n = 38) 500–1000 mg q 8–12h N.A.
Cephalexin (n = 16) 500 mg q 6h N.A.
Cefpodoxime (n = 17) 200–400 mg q12h N.A.
Ciprofloxacin (n = 337) 500–750 mg q12h N.A.
Levofloxacin (n = 171) 500–750 mg q24h N.A.
Moxifloxacin (n = 10) 400 mg q24h N.A.
TMP-SMX (n = 99) 160–320 mg q6–12h N.A.
Sessa Subtherapeutic dosing: No. (%)
FQ/TMP-SMX 2/57 (3.51)
ß-lactams 45/151 (29.8)

Abbreviations: FQ, fluoroquinolone; TMP-SMX, trimethoprim-sulfamethoxazole.