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. 2019 Sep 18;151(10):1213–1230. doi: 10.1085/jgp.201912374

Figure 2.

Figure 2.

The density of MEC-4 channel puncta decreases with distance from the cell body. (A) mNeonGreen-tagged MEC-4 protein localizes to puncta along the entire sensory neurite. White boxes show segments distal (left) and proximal (right) to the ALMR cell body (asterisk). Fluorescence intensity profiles of the segments show a lower density of puncta (peaks) in the distal segment than in the proximal segment. Similar images were obtained from a total n = 51 ALM neurons; anterior is to the left; scale bar = 50 µm; a.u., arbitrary units. (B) IPI increases with distance from the cell body. Average IPI (± SD, top) and individual IPI values (bottom) as a function of normalized distance from the ALM cell body; a total of n = 5,783 IPIs measured from n = 51 ALM neurons. (C) Comparison of the distribution of global IPI values (left; mean = 3.62 µm, mode = 2.23 µm, SD = 2.20 µm) and IPI values derived from arbitrary (right, light blue; mean = 3.83 µm, mode = 2.39 µm, SD = 2.32 µm) or distance-constrained (right, green; mean = 2.97 µm, mode = 2.02 µm, SD = 1.61 µm) samples of 100-µm segments.