Figure 8. . Potentiation of antimicrobial photodynamic inactivation by addition of KI.

Bacteria (10(8) colony-forming unit/ml), tetracyclines (3 μM), exposed to 10 J/cm² of UVA or blue light with the addition of different concentrations of KI. Cells were either present during light (in format), centrifuged before addition of KI and light (spin format), or added after light (after format). Controls (light alone or light + KI) showed no killing (data not shown). (A) Gram-positive MRSA with doxycycline excited by UVA; (B) MRSA with demeclotetracycline excited by blue light; (C) Gram-negative E. coli with doxycycline excited by UVA light; (D) E. coli with demeclotetracycline excited by blue light.

DMCT: Demeclocycline; DOTC: Doxycycline; KI: Potassium iodide; MRSA: Methicillin-resistant Staphylococcus aureus; UVA: Ultraviolet light.

Reproduced from [74].