Figure 1. Figure1: Cytotoxic effect of Nitroglycerine and Valproic acid on K562 cell line. a: Effect of Nitroglycerine on K562 cell line. The cell viability has decreased after treatment with different concentration of nitroglycerine. The most cytotoxic effect was observed in 200 μM at 72 hours after treatment (p<0.05). b: Effect of Valproic acid on K562 cell line. Treatment with different concentrations of valproic acid decreased cell viability, as understood the drug effect is time- and dose-dependent. The most cytotoxic effect was observed in 100 μM at 72 hours after treatment. Different letters indicate significant differences between groups (p<0.05). c: Effect of cisplatin on K562 cell line as a positive control. Cisplatin in all applied concentrations reduce cell viability. d: Cytotoxic effects of NG (200 μΜ), VPA (100 μΜ), NG+VPA (150 μΜ) and Cisplatin (8 μM) on normal PBMC cells for 72 h (*)= p≤0.05, (**) = p≤0.01.