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. 2019 Oct;60(10):1474–1482. doi: 10.2967/jnumed.119.226423

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© 2019 by the Society of Nuclear Medicine and Molecular Imaging.

Immediate Open Access: Creative Commons Attribution 4.0 International License (CC BY) allows users to share and adapt with attribution, excluding materials credited to previous publications. License: https://creativecommons.org/licenses/by/4.0/. Details: http://jnm.snmjournals.org/site/misc/permission.xhtml.

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FIGURE 7. — (A) Representative coronal maximum-intensity projections of SPECT images of MDA-MB-231 tumor xenograft–bearing SCID mice, 24 h after administration of ¹¹¹In-LF^E687A, alone or in combination with (left to right) PA-L1, PA-L1 and excess of unlabeled LF^E687A, PA-U7, PA-WT, or no PA protein. Tumors are encircled (B) Ex vivo biodistribution showing tumor uptake of ¹¹¹In-LF^E687A in different experimental groups. b = bladder; h = heart; l = liver; s = spleen; t = tumor. **P < 0.01. ****P < 0.0001.