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. 2019 Sep;23(Suppl 3):S215–S220. doi: 10.5005/jp-journals-10071-23256

Table 6.

Advantages and disadvantages of blood and pharmacological products

Blood Products Factor concentrates
Advantages
  • FFP contains all factors including vWF and factor XIII

  • Well studied and included in standardized massive transfusion protocols (MTP)

  • Effective volume therapy in shock patients

  • Relatively cheap

Disadvantages
  • Low concentration

  • Transfusion related risks

  • Requires cross matching

  • Large fluid load

  • Shorter storage life

  • Thawing takes time and not immediately available

Advantages
  • High concentration of factors

  • Few transfusion related complications

  • No cross match required

  • Small fluid volumes and hence no hemodilution

Disadvantages
  • Not all factors available

  • High costs

  • Point of care testing required

  • Need parallel fluid resuscitation for volume loss