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. 2019 Oct 10;17:339. doi: 10.1186/s12967-019-2087-9

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Total SNVs detected in plasma. a The distribution of all detected SNVs and non-silent mutations during platinum treatment was shown in the panel. The y-axis represented the mutation number. Each box represented each group and each dot was on behalf of one sample. b A comparison of non-silent mutations between platinum sensitive (SDa/PR) and platinum insensitive (PD/SD/SDb). The x-axis represented the mutation number detected in plasma and the y-axis represented the groups. c The distribution of C>G substitution subtype during chemotherapy. The y-axis represented the number of C>G substitution subtype in the two panel on the left with each dot representing one sample, whereas y-axis on behalf of the VAFs in the two panel on the right with each dot representing one mutation