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. 2019 Oct 10;17:339. doi: 10.1186/s12967-019-2087-9

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Signatures of mutational processes in 27 pre-chemotherapy plasma samples. Barplot showed the prevalence of platinum associated signature for four independent cohorts on the left. Total SNVs contributed to platinum associated signature (coral1) and smoking associated signature (darkolivegreen3) was shown in the panel on the right. Vertical axis represented the samples. *Represented BRCA1/2 mutant. Those samples with sensitive response were indicated in darkslateblue and smokers were indicated in darkslategrey