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. 2019 Oct 10;17:339. doi: 10.1186/s12967-019-2087-9

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Landscape of potentially clinically actionable variants in plasma of LUAD. a Landscape of non-silent mutations of common reporter genes and three important pathway genes during chemotherapy. The y-axis represented the gene, whereas x-axis on behalf of samples. Different color showed different mutant type of non-silent mutations. b Plasma VAFs of key pathways during platinum-based chemotherapy