Fig. 7.

Panel a Mid ventricular short axis slice from in-vivo imaging showing antero-septal scar. Panel b Short axis slice at same level as panel A with segmentation of healthy myocardium (yellow) and scar (red) superimposed on imaging. Panel c Mid ventricular short axis slice from ex-vivo imaging at corresponding level to panel A/B. White arrows indicate the epicardial aspect of the interventricular septum, with the adjacent collapsed right ventricular cavity. Panel d Short axis slice at same level as panel C with segmentation of in-vivo imaging superimposed. Note is made of the shrinkage of the left ventricular cavity despite the printed scaffold. Panel e Mid ventricular short axis slice from ex-vivo imaging at corresponding level to panel C/D following non-rigid registration to correct for residual morphological change. White arrows indicate the epicardial aspect of the interventricular septum, with the adjacent collapsed right ventricular cavity. Panel f Short axis slice at same level as panel E with segmentation of in-vivo imaging superimposed demonstrating correction of residual morphological change following non-rigid registration