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. 2019 Aug 26;3(11):1969–1978. doi: 10.1210/js.2019-00243

Figure 2.

Figure 2.

PIT-1 protein was processed in the antigen presentation pathway in GH3 cells. (A) Schematic diagram of MHC/HLA class I antigen presentation pathway. (B) PIT-1 detected by the anti–PIT-1 antibody [15] demonstrated a colocalization with MHC class I molecules. (C) PIT-1 detected by the patient serum [2] demonstrated a colocalization with MHC class I molecules. (D) PIT-1 colocalized with calnexin, which is an ER marker. (E) PIT-1 colocalized with GM130, which is a Golgi apparatus marker. Arrowheads indicate merged signals with each protein. Scale bar, 10 µm.