Fig. 2.

Pharmacological agents identify different nicotinic responses. A, Fast-decaying nicotinic currents elicited by choline in four interneurons under control condition (the largest response in each) and after 5–10 min exposure to different inhibitory agents (the smallest response in each). B, Slowly decaying nicotinic currents elicited by ACh in four interneurons under control condition (the largest response in each) and after 5–10 min exposure to different inhibitory agents (the smallest response in each). C, Choline-induced responses in a current-clamped interneuron before (first trace) and after 5 min continuous exposure to choline (100 μm) (second trace). ACh-induced responses in another current-clamped interneuron before (first trace) and after 5 min continuous exposure to DHβE (fourth trace).