Fig. 6.

Nicotinic agonists increase the frequency of PSCs. Analysis of the peak amplitude, 10–90% rise time, and interevent intervals of PSCs that occurred either spontaneously (270 sec data) or in response to choline (40 sec data, two pulses applied) and ACh (20 sec data, one pulse applied) in a CA1 interneuron. Data were from the same experiment as illustrated in Figure 5B.A, Cumulative distribution of peak amplitude, rise time, and interevent intervals of events recorded under different experimental conditions. This representation clearly shows that nicotinic agonists increased the frequency but not other parameters of the PSCs. B, Several PSCs were averaged: 304 spontaneous events, 81 events recorded in the presence of choline, and 57 events recorded in the presence of ACh. These averaged traces show very little differences in their decay phase.