Immunostaining of different mGluR subtypes in transverse retinal sections of wild-type (+/+) and mGluR6 knock-out (−/−) mice. Immunoreactivities of mGluR1α (A,B), mGluR5a (C, D), mGluR2 (E, F), mGluR4a (G,H), mGluR8 (I,J), and mGluR7a (K,L). Note that mGluR7a immunoreactivity can be seen at the OPL of mGluR6 knock-out (L) but not in wild-type (K) mice. For other subtypes, no difference in the immunostaining patterns is observed between the two genotypes. Asterisks in G–J show immunostaining of blood vessels. Scale bars, 20 μm.