Table 3.
Postoperative characteristics (after primary surgery) of cases with failed DSAEK undergoing re-DSAEK or penetrating keratoplasty
| Postoperative factor | Re-DSAEK group (n=62) | PKP group (n=32) | P |
|---|---|---|---|
| Lenticule thickness (μm)1 | 171.5±51.5 | 170.1±60.7 | 0.9 |
| Host thickness (μm)1 | 688.3±110.9 | 877.6±262.8 | <0.001 |
| Rebubbling2 | 23 (37.1%) | 10 (31.2%) | 0.65 |
| Secondary glaucoma2 | 24 (38.7%) | 21 (65.6%) | 0.017 |
| Peripheral anterior synechiae2 | |||
| </= 1 quadrant | 9 (14.5%) | 19 (59.4%) | |
| >1 quadrant | 9 (14.5%) 0 | 11 (34.4%) 8 (25%) | 0.029 |
| Glaucoma treatment2 | |||
| Medical | 24 (100%) | 12 (57.1%) | <0.001 |
| Surgical | 0 | 9 (42.9%) | |
| Trabeculectomy | 5 (23.8%) | ||
| Glaucoma drainage devices | 4 (19.1%) | ||
| Lens status2 | |||
| Phakic | 1 (1.6%) | 6 (18.8%) | |
| Pseudophakic | 60 (96.8%) | 25 (78.1%) | |
| PCIOL | 57 (91.9%) | 9 (28.1%) | <0.001 |
| SFIOL | 3 (4.8%) | 12 (37.5%) | |
| ACIOL | 0 | 4 (12.5%) | |
| Aphakic | 1 91.6%) | 1 (3.1%) | |
| Stromal scarring2 | 19 (30.6%) | 23 (71.8%) | <0.001 |
| Cause of graft failure2 | |||
| Primary | 34 (54.8%) | 12 (37.5%) | 0.13 |
| Secondary | 28 (45.2%) | 20 (62.5%) | |
| Graft infection | 0 | 3 (9.4%) | |
| Graft rejection | 10 (16.1%) | 0 | |
| Uncontrolled glaucoma | 6 (9.7%) | (18.8%) | |
| Endothelial cell loss | 12 (19.3%) | 11 (34.3%) | |
| Time interval between primary DSAEK and graft failure (months)3 | 0 (0-10) | 0.33 (0-10) | 0.59 |
| Time interval between graft failure and repeat keratoplasty (months)3 | 8 (0.15-19) | 16 (1-36) | <0.001 |
DSAEK=Descemet stripping automated endothelial keratoplasty; PKP=Penetrating keratoplasty; PCIOL=Posterior chamber intraocular lens; SFIOL=Scleral fixated intraocular lens; ACIOL=Anterior chamber intraocular lens. 1Results displayed as mean±standard deviation. 2Results displayed as number of cases (percentage). 3Results displayed as median (range)