Skip to main content
. 2019 Oct;67(10):1599–1605. doi: 10.4103/ijo.IJO_1952_18

Table 3.

Comparison of the present study with existing literature

Characteristics Xie et al., 2001 Rogers et al., 2013* Sharma et al., 2013 Present study
Number of transplants 108 32 506 (106/506 eyes had Fungal keratitis) 198
Study period 4 years (1996-1999) 10 years (2001-2011) 10 years (1999-2009) 3 years (2008-2010)
Country China USA India India
Age (years) <20: 3.7%
21-40: 48.2%
41-60: 39.8%
>60: 8.3%
Median: 59
Range: 16-86
Mean: 45.6
Range: 14-72
Mean±SD: 45±14.3
Male: Female 1.8:1 0.9:1 0.7:1 1.9:1
Infiltrate size (mm) <6: 13.9%
6.1-8: 36.1%
>8: 50%
Minimum median diameter of infiltrate 1.50 mm Mean 8.19±2.13 <6: 20.7%
6-8: 38.9%
>8: 40.4%
Donor tissue size (mm) 7.25-8: 40%
8.5-9: 25.9%
>9: 33.3%
Not available <9: 44%
9-11: 39%
>11: 16.6%
8-9 mm - 17.6%
9-11 mm - 54.5%
>11 mm - 24.7%
Organism Aspergillus spp: 14.4%
Candida spp: 9.3%
Fusarium spp: 65%
Penicillium spp: 4.1%
Unidentified: 7.2%
Alternaria spp: 9.4%
Aspergillus spp: 12.5%
Candida spp: 28.1%
Fusarium spp: 34.4%
Other filamentous fungi: 12.5%
Other yeasts: 3.1%
Fungal: 20.9%
(Aspergillus spp. Most common) Bacterial: 31% Mixed Bacterial and Fungal: 6.9% Acanthamoeba: 1.6%
Aspergillus flavus: 32.3%
Acremonium spp: 17.7%
Fusarium spp: 15.7%
Cladosporium spp: 0.5%
Unidentified hyaline: 27.2%
Curvularia spp: 1%
Dematiaceous fungi: 5.1%
Scedosporium spp: 0.5%
Clear cornea 79.6% at an average follow-up of 18.3 months 53.1% at a median follow-up of 25 months Not available 12.3% at a follow up of 12 months, 10.6% at 24 months and 6.1% at 48 months
Recurrence rate 7.4% 9.4% Reinfection noted in 12.6% 10.1%
Graft failure 13.9% at 24 months 46.9% at 70 months Not available 71.7% at 60 months

*Eyes that were treated with medical therapy and therapeutic keratoplasty were included in the comparison