Table 2. Correlation between the clinicopathologic variables and CELSR3 mRNA expression in liver cancer.

Parameters	Groups	N	CELSR3 expression				χ2	P value
			High	%	Low	%
Age (years)	≥60	203	110	49.77	93	61.59	5.052	0.025*
	<60	169	111	50.23	58	38.41
Gender	Female	121	57	30.48	64	34.41	0.656	0.418
	Male	252	130	69.52	122	65.59
Family history	Yes	112	54	33.96	58	35.80	0.120	0.729
	No	209	105	66.04	104	64.20
Tumor status	With tumor	112	65	38.24	47	26.70	5.252	0.022*
	Tumor free	234	105	61.76	129	73.30
Radiation therapy	No	341	173	97.74	168	97.11	0.139	0.71
	Yes	9	4	2.26	5	2.89
Histologic grade	Grade 1	55	24	12.90	31	17.03	2.187	0.534
	Grade 2	178	90	48.39	88	48.35
	Grade 3	123	67	36.02	56	30.77
	Grade 4	12	5	2.69	7	3.85
Vascular invasion	Macro	16	8	5.19	8	4.91	0.136	0.934
	Micro	94	47	30.52	47	28.83
	None	207	99	64.29	108	66.26
TNM Stage	Stage I	172	73	40.78	99	58.24	14.317	0.003*
	Stage II	87	51	28.49	36	21.18
	Stage III	85	54	30.17	31	18.24
	Stage IV	5	1	0.56	4	2.35
T classification	T1	182	76	40.64	106	57.61	13.367	0.010*
	T2	95	55	29.41	40	21.74
	T3	80	50	26.74	30	16.3
	T4	13	6	3.21	7	3.80
	TX	1	0	0.00	1	0.54
N classification	N0	253	131	70.43	122	65.59	1.025	0.599
	N1	4	2	1.08	2	1.08
	NX	115	53	28.49	62	33.33
M classification	M0	267	134	71.66	133	71.51	1.040	0.594
	M1	4	1	0.53	3	1.61
	MX	102	52	27.81	50	26.88
Residual tumor	R0	326	165	89.67	161	88.46	1.097	0.778
	R1	17	8	4.35	9	4.95
	R2	1	0	0.00	1	0.55
	RX	22	11	5.98	11	6.04
Vital status	Living	243	107	57.22	136	73.12	10.381	0.001*
	Deceased	130	80	42.78	50	26.88
Relapse	Yes	176	101	62.35	75	46.88	7.774	0.005*
	No	146	61	37.65	85	53.12

Notes.

^*P < 0.05.

CELSR3, Cadherin EGF LAG seven-pass G-type receptor 3.