Fig. 4.

Cell viability of human UBC cells treated with UNC0642. a Chemical structure of UNC0642. b Cytotoxicity of UNC0642 in the human UBC cell lines T24, J82, and 5637 after treatment for 72 h. The assays were performed in triplicate, and the results are presented as the mean ± SD. c UNC0642 suppressed the activity of G9a protein according to detection of the level of H3K9me2. T24 and J82 cells were treated with UNC0642 for 24 h at the indicated concentration. β-Actin was used as the loading control