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. 2019 Jun 28;40(10):1364–1372. doi: 10.1038/s41401-019-0269-x

Table 1.

Assembly analysis of AgUricases

Subunits ΔGdiss (kcal/mol) ASA, Å2 BSA, Å2
Wild-type Tetramer 77.6 39484 25175
A–D dimer 33.4 25324 7045
B–C dimer 31.5 25114 7176
K12C–E286C Tetramer 77.7 38389 30069
A–D dimer 59.1 25869 8126
B–C dimer 49.8 25988 8475

ASA accessible surface area, BSA buried surface area, ΔGdiss free energy of disassociation