Fig. 4.

Determination of apoptosis in atherosclerotic plaque of ApoE^−/− and ApoE^−/−;Nampt-Tg mice. a Representative images of TUNEL staining in atherosclerosis plaque and quantitative analysis. **P < 0.01 vs. ApoE^−/−. Scale bar, 100 μm. b–d Activities of caspase-3 (b), caspase-8 (c) and caspase-9 (d) were measured. **P < 0.01 vs. ApoE^−/−