Fig. 5.

TNF-α, but not IL-1β, is activated in atherosclerotic plaque of ApoE^−/−;Nampt-Tg mice. a Infiltrated macrophages were evaluated by F4/80 staining. **P < 0.01 vs. ApoE^−/−. b TNF-α immunohistochemistry staining and quantitative analysis. *P < 0.05 vs. ApoE^−/−. c IL-1β immunohistochemistry staining and quantitative analysis. Scale bar, 100 μm. d Serum TNF-α level in ApoE^−/− and ApoE^−/−;Nampt-Tg mice. NS no significance