Fig. 2.

IMB17–15 markedly prevented weight gain due to HFD feeding and improved liver histology in HFD-fed hamsters. a Relative body weight gain in the control, HFD + NS and HFD + IMB17–15 groups. b The liver weight to body weight ratio after 21 days. Double-blinded quantitative assessment of (c) Hepatic inflammation showed that IMB17–15 ameliorated HFD-induced histopathological changes. d Liver pathological changes were detected by H&E staining (magnification × 400). H&E hematoxylin and eosin, HFD high fat diet. The values are expressed as the mean ± SD (n = 6 in each group), ^##P < 0.01 versus the control group, *P < 0.05, **P < 0.01 versus the HFD + NS group; ANOVA followed by Duncan's multiple range tests