Irisin improved cardiac function and reduced infarct size in post-MI mice. a1 Representative images of M-mode echocardiographic images at 28 days post-MI. a2–5 The left ventricle ejection fraction (EF), fractional shortening (FS), diastolic left ventricle internal diameter (LVIDd) and systolic left ventricle internal diameter (LVIDs) after MI at 7, 14, and 28 days post-MI. b Representative images and quantification of infarct size analyzed by TTC staining. n = 12, *P < 0.05 vs. control