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Minocycline inhibits a MCP-1 and b IL-1β secretion induced by I/R injury in vivo. The protein levels of MCP-1 and IL-1β in the ischemic myocardium were assessed by a Bio-Plex ProTM kit. The values represent the mean ± SEM, n = 6 rats per group; *P < 0.05, **P < 0.01 compared with the Sham group; #P < 0.05, ##P < 0.01 versus the I/R model group. MCP-1, monocyte chemoattractant protein-1
