Fig. 4.

Rab7 receptor antagonist promotes brain functional recovery in rats. a Rab7 receptor antagonist reduces brain atrophy at 28 days after reperfusion following tMCAO for 90 min. Quantitative analysis of the residual right brain volume/left brain volume. b The grip strength test; The cylinder test; The 6-point scale neurological score test. Mean ± SD. n = 10. ^##P < 0.01 vs. sham group; ^**P < 0.01 vs. tMCAO group. Statistical analysis was carried out with a two-way ANOVA followed by a post-hoc Tukey test for multiple comparisons and Student’s t-test for two groups. Ordinal values were analyzed by two-way analysis of variance (ANOVA) using Bonferroni’s post-hoc correction