Table 1. .

Case Reports of Disseminated Sporotrichosis in Immunocompetent Individuals

Publication	Location	Age/Sex	Sites Involved	Risk Factor(s)	Treatment Regimen	Outcome
Campos-Macias et al. (2006) [13]	Japan	74/M	Skin (multiple sites) Lymph nodes Joints – arthritis, ankylosis, bursitis	None identified	Itraconazole 400 mg/d × 4 mo, then stopped prematurely Itraconazole 400 mg/d restarted, but taken incorrectly (200 mg/d)	Final outcome not provided
Yap (2011) [14]	Malaysia	70/F	Skin (multiple sites) Systemic – fevers, night sweats, wt loss	Gardening Pet cats	Amphotericin 0.7 mg/kg/d for 2 wk, followed by itraconazole 400 mg/d for 8 mo	Resolution
Ribeiro et al. (2015) [15]	Brazil	5/M	Skin (multiple sites) Joints – polyarthritis	None identified	Amphotericin (dose unknown) for 2 wk, followed by itraconazole (dose unknown) for 45 d	Resolution
Hassan et al. (2016) [6]	USA	56/M	Skin Joints – bilateral arthritis, bursitis Lungs – pleural effusions Eyes Systemic – fevers, wt loss	Farmer Alcohol use Type 2 DM	Liposomal amphotericin 3 mg/kg/d for 1 mo; discharged on itraconazole	Patient lost to follow-up
Hessler et al. (2017) [16]	California, USA		CNS – chronic meningitis Lungs Systemic – fevers No skin lesions or joint involvement	Construction worker	Itraconazole for 12 mo	Resolution

Abbreviations: CNS, central nervous system; DM, diabetes mellitus.