Table 3. Azithromycine degradation constant rate k values at different pH levels.
“k (10−4)” | ||||||
---|---|---|---|---|---|---|
Time (hour) | pH 4 | pH 5 | pH 6 | pH 7 | pH 8 | pH 9 |
1 | 1820 ± 15e | 1010 ± 5e | 430 ± 4d | 110 ± 2e | 260 ± 2e | 60 ± 0.6e |
3 | 763 ± 7d | 623 ± 2cd | 333 ± 2c | 80 ± 0.6d | 160 ± 2d | 13 ± 0.3a |
6 | 678 ± 5c | 578 ± 4c | 366 ± 3cd | 50 ± 0.4c | 93 ± 0.8c | 40 ± 0.2d |
12 | 422 ± 2ab | 344 ± 4b | 215 ± 2b | 15 ± 0.2b | 58 ± 0.6b | 30 ± 0.2c |
24 | 391 ± 2a | 221 ± 2a | 134 ± 2a | 7 ± 0.1a | 31 ± 0.4a | 20 ± 0.1ab |
Different letters indicate statistically significant differences at P < 0.05 according to a Tukey’s honest significant difference post hoc test. Values are mean ± standard errors of triplicate samples.