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. 2019 Oct 10;14(10):e0223475. doi: 10.1371/journal.pone.0223475

Table 3. Azithromycine degradation constant rate k values at different pH levels.

k (10−4)”
Time (hour) pH 4 pH 5 pH 6 pH 7 pH 8 pH 9
1 1820 ± 15e 1010 ± 5e 430 ± 4d 110 ± 2e 260 ± 2e 60 ± 0.6e
3 763 ± 7d 623 ± 2cd 333 ± 2c 80 ± 0.6d 160 ± 2d 13 ± 0.3a
6 678 ± 5c 578 ± 4c 366 ± 3cd 50 ± 0.4c 93 ± 0.8c 40 ± 0.2d
12 422 ± 2ab 344 ± 4b 215 ± 2b 15 ± 0.2b 58 ± 0.6b 30 ± 0.2c
24 391 ± 2a 221 ± 2a 134 ± 2a 7 ± 0.1a 31 ± 0.4a 20 ± 0.1ab

Different letters indicate statistically significant differences at P < 0.05 according to a Tukey’s honest significant difference post hoc test. Values are mean ± standard errors of triplicate samples.