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. 2019 Oct 10;14(10):e0222833. doi: 10.1371/journal.pone.0222833

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© 2019 De Gaetano, Hardy

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 13 — Long-term (lifetime) model-predicted changes in DPP-measured variables and in HbA1c for the three DPP treatment arms. The curves refer to no intervention (black), Placebo (blue), Metformin (red), Intensive LifeStyle (green). Top panels refer to glycemia (from left to right fasting glycemia, glycemia at 30 minutes during OGTT and glycemia at 2 hours during OGTT). Bottom panels are, from left to right, fasting insulinemia, insulinemia at 30 minutes during OGTT, glycated hemoglobin.