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. 2019 Oct 10;14(10):e0223191. doi: 10.1371/journal.pone.0223191

Table 2. Distribution of the LGALS9 alleles and genotypes in patients with RA and healthy individuals.

SNP genotype RA Control p-value RR OR (95%IC)
rs4795835 (N = 154) % (N = 195) %
CC 103 66.88 109 55.89 0.063 0.83 0.65 (0.42–1.01)
CT 44 28.57 80 41.03 0.025 1.25 1.69 (1.08–2.64)
TT 7 4.54 6 3.07 0.415 0.76 0.59 (0.20–1.75)
CT and TT 51 33.11 86 44.10 0.063 1.20 1.52 (0.98–2.34)
C- allele 250 81.16 298 76.41 0.233 0.90 0.79 (0.54–1.13)
T-allele 58 18.83 92 23.58 0.233 1.10 1.26 (0.87–1.81)
rs3763959 (N = 105) % (N = 192)
AA 7 6.67 29 15.10 0.040 1.29 2.49 (1.05–5.90)
AG 40 38.09 96 50 0.052 1.18 1.62 (1.00–2.63)
GG 58 55.23 67 34.89 0.0009 0.73 0.43 (0.26–0.70)
AG and GG 98 93.33 163 84.89 0.040 0.77 0.40 (0.16–0.95)
A-allele 54 25.71 154 40.10 0.0001 1.83 4.20 (2.90–6.09)
G-allele 156 74.28 230 59.89 0.0004 1.55 1.93 (1.33–2.80)
rs4239242 (N = 109) % (N = 192)
TT 17 15.59 10 5.20 0.0032 0.54 0.28 (0.12–0.64)
TC 21 19.26 127 66.14 0.0001 2.03 7.99 (4.59–13.91)
CC 71 65.13 55 28.64 0.0001 0.55 0.22 (0.13–0.36)
TC and CC 92 84.40 182 94.79 0.0054 1.79 3.36 (1.48–7.64)
T-allele 55 25.22 147 38.28 0.0019 1.21 1.77 (1.23–2.55)
C-allele 163 74.77 237 61.71 0.0019 0.82 0.56 (0.39–0.80)