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. 2019 Oct 10;14(10):e0223470. doi: 10.1371/journal.pone.0223470

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© 2019 Alghofaili et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — Plasma cell-free DNA (cfDNA) was isolated from breast (n = 26) and ovarian cancer (n = 64) patients with various stages and undergoing treatment. Female subjects (n = 50) from healthy individuals of a similar age were selected as controls for breast and ovarian cancer patients. Separate cfDNA comparisons wre made between healthy female controls and the cancers patients by Wilcoxon rank sum test. Highly significant differences (***) were observed between cfDNA levels measured by Qubit fluorometer (ng/ml) of healthy females and breast cancer patients (p = 6.278e-07) and healthy females and ovarian cancer patients (p = 2.708e-11).