Fig 3. Lymphocyte transformation test (LTT) after activation with influenza vaccine.

Results are expressed as the ratio of (A) (%CD4⁺CD69⁺ after influenza vaccine stimulation) / (%CD4⁺CD69⁺ in basal conditions) and (B) (%CD8⁺CD69⁺ after influenza vaccine stimulation) / (%CD8⁺CD69⁺ in basal conditions). Median ratio with IQR are represented for each group. HU, Hydroxyurea; CT, Chronic transfusion; No DMT, No Disease modifying therapy. *p<0.05; **p<0.01; ***p<0.005.