Comparison 1. Antibiotics versus placebo/no antibiotics.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Implant failures	6	1162	Risk Ratio (M‐H, Random, 95% CI)	0.33 [0.16, 0.67]
2 Prosthesis failures	5	1107	Risk Ratio (M‐H, Random, 95% CI)	0.44 [0.19, 1.00]
3 Postoperative infections	6	1162	Risk Ratio (M‐H, Random, 95% CI)	0.69 [0.36, 1.35]
4 Adverse events	6	1162	Risk Ratio (M‐H, Fixed, 95% CI)	1.0 [0.06, 15.85]