5. Random‐effects metaregression analysis of outcomes PAL, PPD, REC.

Characteristic	Outcome	Studies	Slope estimate (SE)	95% CI	Slope	P value
Parallel versus split mouth	PAL	9	0.68 (0.63)	(‐0.81, 2.19)	Emdogain in parallel group trials has higher effect	0.31
Parallel versus split mouth	PPD	9	0.71 (0.66)	(‐0.87, 2.28)	Emdogain in parallel group trials has higher effect	0.32
Parallel versus split mouth	REC	6	0.28 (0.36)	(‐0.72, 1.28)	Emdogain in parallel group trials has higher effect	0.48

CI = confidence interval
 PAL = probing attachment level
 PPD = probing pocket depth
 REC = gingival recession