Table 2.

Comparison of demographics, arrhythmias and echocardiographic parameters between PVC groups.

Variable	PVC Grp 1 (n=599)	PVC Grp 2 (n=82)	PVC Grp 3 (n=81)	PVC Grp 4 (n=83)	P value
Demographics
Males	516 (86%)†	75 (93%)	75 (90%)	79 (96%)*	0.02
Hypertension	428 (71%)	62 (76%)	61 (73%)	56 (68%)	0.66
Diabetes	185 (31%)	32 (39%)	27(32%)	29 (35%)	0.41
CAD	155 (26%)	22 (27%)	30 (36%)	28 (34%)	0.12
Ambulatory ECG
Heart rate (bpm)	75±11	72±11	72±10	74±10	0.08
PAC burden (%)	1.6±2.4	2.5±3.6‡	2.3±3.6	1.4±1.2†	0.03
AF burden (%)	1.2±6.6	1.4±7.8	1.1±6	0.1±0.7	0.55
SVT episodes (No.)	138±1416	331±1869	279±2071	18±62	0.03
Total PVC (No.)	702±2191	20799±9182	48394±20367	252199±41943	0.000
VT episodes (No.)	0.43±5.9‡	0.49±1.4‡	0.69±1.3‡	20±74*†~	0.000
Echocardiographic parameters	(n=296)	(n=49)	(n=48)	(n=40)	P value
LVEF (%)	52.7±9.4	50.2±9.8	47.1±13.5*	44.9±13.9*	0.0001
LVEF < 50%	53 (18%)~‡	14 (29%)	18 (37%)*	17 (42%)*	0.0001
LVEDD (cm)	4.8±1.3	5.0±0.8	5.0±0.8	5.3±0.7*	0.03
LVESD (cm)	3.3±0.7†~‡	3.7±0.9*	3.8±0.9*	4.1±0.9*	0.000
LA (cm)	3.8±0.61†	4.1±0.6*	3.9±0.7	4.1±0.70	0.008

PVC group 1 (< 1%, median (IQR)-0.9 (0.9-0.9), n 600), PVC group 2 (range: 1.1-2.4%, median (IQR)-1.4 (1.1-2.0), n=81), PVC group 3 (range: 2.5-5.8%, median (IQR)-4.1 (3.3-4.9), n=83), PVC group 4 (range: 5.9-44.7%, median (IQR)-14.1 (8.8-19.9), n=82). Data is presented as mean and SD. Note that echocardiographic data includes a lower number of patients since not all had associated 2-D echocardiogram. P value using one-way ANOVA. Significant Bonferroni correction (<0.05) for PVC

^(*)group 1

^(†)group 2

^(~)group 3

^(‡)and group 4.

Grp-Group, LVEF-Left ventricular ejection fraction, LVESD-Left ventricular end systolic diameter, PAC-premature atrial contraction, PVC-Premature ventricular contraction, SVT-Supraventricular tachycardia, VT-Ventricular tachycardia.