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. 2019 Oct 10;10(10):776. doi: 10.1038/s41419-019-2006-2

Fig. 7. RGC-32 silencing in macrophages inhibited tumor growth, decreased COX-2 and Ki67 expression of xenografts.

Fig. 7

HCT-116 cells were co-injected with RGC-32-silenced macrophages or control macrophages to establish a subcutaneous tumor model. a–c Tumor sizes and weights were smaller after co-injection of RGC-32-silenced macrophages and HCT-116 cells as compared with that after co-injection of control macrophages and HCT-116 cells. d A lower expression of COX-2 and Ki67 was detected in tumor from co-injection of RGC-32-silenced macrophages and HCT-116 cells (100×). e Schematic representation of interactions between colon cancer cells and macrophages through RGC-32. Each bar represents the mean ± SD (*p < 0.05, **p < 0.01)