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. 2019 Oct 10;9:14551. doi: 10.1038/s41598-019-51211-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Kaplan–Meier survival curves showing the duration of imatinib mesylate treatment (yellow line) and progression free survival (PFS; blue line) in patients with locally advanced or recurrent diffuse-type TGCT. PFS was calculated from the date imatinib mesylate was started to the date of disease progression or death. The shaded areas are 95% confidence intervals (CI). Over half of the patients discontinued IM within a year. The overall PFS after 5 years was ~50%.