Table 1.
Summary of the antibody characterization performed in this study.
| Breed | Age (years) | Sex | Clinical signs/diagnosis | Whole IgG (mouse) | Fc (mouse) | F(ab’)2 (mouse) | Cross-reactivity | Isotype |
|---|---|---|---|---|---|---|---|---|
| BMD | 3 | MN | − | + | − | + | − | IgA, IgG, IgM |
| BMD | 3 | FN | − | + | − | − | − | IgG |
| BMD | 1 | F | − | + | − | + | − | IgM |
| BMD | 1 | F | − | + | − | + | Goat | N/A |
| LR | 8 | M | − | + | − | + | −* | N/A |
| BMD | 4 | M | − | + | − | − | − | IgM |
| BMD | 5 | FN | Lipoma | + | − | + | − | IgA, IgG, IgM |
| BMD*** | 8 | MN | Protein losing enteropathy | + | + | − | − | IgG |
| BMD | 10 | FN | Anterior cruciate ligament injury | + | − | − | Goat, sheep | N/A |
| BMD | 1 | F | Gastric dilatation volvulus | + | + | − | − | − |
| BMD | 6 | M | Mast cell tumour | − | + | − | − | IgM |
| LR*** | 3 | MN | Polyuria/polydipsia | − | + | − | −** | N/A |
Isotyping was not performed on samples that contained inadequate volumes, or that reacted with goat IgG. Abbreviations: BMD, Bernese mountain dog; LR, Labrador retriever; M, male; F, female; N, neutered. *Not tested for reactivity to chicken IgY. **Not tested for reactivity to rabbit IgG or chicken IgY. ***Two samples from this dog were analyzed.